Perinatal hypoxic-ischemic encephalopathy (EHIP) Diagnosis

Perinatal hypoxic-ischemic encephalopathy (EHIP)
Diagnosis

Issue diagnosis of hypoxic-ischemic encephalopathy is based on history and clinical examination of the newborn.
Anamnesis must establish:
- complications in pregnancy, labor, birth;
- cardio-fetal monitoring;
- fetal acid-base status;
- Apgar score at 5, 10, 20 minutes;
- placental pathology.
The cornerstone of diagnosis is clinical neurological assessment during the immediate post-natal period, which must include examination and identification of associated metabolic disorders, and evaluation of lesions in other organs.

Laboratory examinations include:
- measurement of intracranial pressure;
- measurement of cerebral blood flow by Doppler ultrasound;
- electroencephalogram (EEG);
- evoked potentials;
- computed tomography;
- Trans ultrasound;
- nuclear magnetic resonance.

Explorations biochemical investigations focused on the following: hypoglycemia, hypocalcemia, hyponatremia, hyperammonemia.

Exploring the diagnosis of acid-base metabolic acidosis.
Highlights the increased creatine enzyme markers in blood and cerebrospinal fluid (CSF).
Lumbar puncture performed to determine the presence of liquid high blood pressure, or bleeding xantocrom with proteinorahie over 1, 50 g% o.