Hand, foot and mouth disease
Signs and symptoms
The most commonly affected are children under 10 years and epidemics may develop in close contact and their families. Proximativ Incubation lasts a week, patients report the mouth or throat ulcerations. It develops malaise, fever and vomiting. Originally appearing macular lesions of the oral mucosa, tongue and hard palate. These mucosal lesions rapidly progress to vesicles that erode and become surrounded by an erythematous halo. Skin lesions present as soft patches or blisters with erythematous base develops in approximately 75% of patients. For 24-48 hours 38-39 degrees fever is present.
Atypical clinical manifestations.
Miina-foot-mouth disease caused by Coxsackie virus mutant with aseptic meningitis rarely presents itself. Disease caused by EV-71 type has a high incidence of neurological damage including poliolike syndrome, aseptic meningitis, encephalitis, encephalomyelitis, acute cerebral ataxia, acute transverse myelitis, Guillain-Barre syndrome and benign intracranial hypertension opsomioclonus.
Miina foot mouth disease is the most common cause of ulcers in the pediatric population. Yellow ulcers surrounded by red halo characteristic oral lesions. They occur mostly on the surface of oral mucosa and mouth, but can be observed on the tongue, palate, uvula, pillars tonsilari historical or gums. Girl gingivostomatita perioral herpetic lesions are nacaracteristice. Determine and herpangina Coxsackie virus, described as posteriorare oropharyngeal lesions and without palatal exanthema associated. Oral ulcers are painful. Children under five years are more symptomatic than older patients invirsta.
Exanthema dorsal surface but frequently involve typical surface may include palm, interdigital, palm of hands and feet. These lesions may be asymptomatic or pruritic. His debut as erythematous macules that rapidly progress to vesicles and thin-walled gray erythematous base. In young children this may be observed on the trunk and thighs. Redness is usually self-limiting and lasts about 3-6 days. Case reports showing chronic skin lesions, and subacute recurrences.
Disease progression The disease has an overall recovery rate. However, EV71 virus has recently been involved in several recurrent epidemics of severe complications and death. Complications are rare but can occur any pruritic erythema a secondary skin infection. Severe complications may occur when is this affecting the central nervous system and cardiopulmonary. These sequelae include dysphagia, limb weakness, cardiopulmonary failure and even death. Although death is rare is most often due to pulmonary hemorrhage or edema. Enteroviruses are a group that causes aseptic meningitis and encephalitis, however Miina-foot-mouth disease is usually associated with meningitis.
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