Perinatal hypoxic-ischemic encephalopathy (EHIP) Clinical signs

Perinatal hypoxic-ischemic encephalopathy (EHIP)
Clinical signs

Depending on the severity of disease symptoms is diverse, being divided into three different levels.
Level I of disease shows the following symptoms: restlessness, normal tone, poor sucking, decreased Moro reflex, mydriasis, absence seizures.
Grade II of hypoxic-ischemic encephalopathy shows symptoms: lethargy or sleepiness, mild hypotonia, poor sucking or absent, weak Moro, miosis, focal or multifocal seizures.
Grade III of the disease is characterized by clinical signs: stupor that responds only to strong stimuli, placidity, cerebration intermittent sucking absent Moro absent pupillary light reflex decreased.


In mild (Grade I) electro encephalogram (EEG) is normal and duration of symptoms is less than 24 hours.
In mild form (grade II) show microvolt EEG delta and theta, with duration of symptoms between 2-14 days, and severe (Grade III) is suppressed brain power, duration of symptoms in weeks.