The first step in diagnosis is to the patient's physical examinationto highlight the characteristic signs of muscular dystrophy.
Laboratory analysis consists in the concentration of creatineresearch, a chemical released in the process of necrosis(destruction) of cells. An increased concentration of creatine allowsdiagnosis of muscular dystrophy.
For diagnosis of Duchenne myopathy may be investigated and the level of dystrophin in muscle. A very low level of this protein willindicate the presence of DMD.
Muscle biopsy is the best method of diagnosis. During thismedical procedure, is take a sample of tissue for examinationunder a microscope. In the case of muscular dystrophy, willhighlight microscopic muscle fiber degeneration. As the disease,muscle tissue necrosis (dead) will be replaced by connectivetissue or fat.
Muscle functioning can be verified with electromyography (EMG) -test that measures electrical activity of muscles.
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