Warts (warts)

Warts (warts)

    * Introduction
    * Signs and symptoms
    * Treatment of warts
Nongenitale warts or warts are benign proliferations of skin and mucous membranes caused by human papilloma virus. Today more than 100 types of this virus were identified. Certain types of the virus tends to occur in specific anatomical areas, however, warts can occur in any location on the body. The main clinical manifestation of infection with human papilloma virus-HPV include common warts, genital warts, flat warts and warts deep palmoplantare (mimecia) Less common manifestations of HPV infection include focal epithelial hyperplasia, Heck disease, plantar epidermodisplazia veruciforma and cysts.
Warts are transmitted by direct or indirect, and predisposing factors include alterations in normal epithelial barrier. Treatment can be difficult, and frequently recurring failures. Many warts resolve spontaneously within a few years. A small number of HPV types is associated with the development of neoplasms, including types 6, 11, 16, 18, 31 and 35. Malignant transformation is most commonly seen in patients with genital warts and the immunocompromised. HPV types 5, 8, 20 and 47 have oncogenic potential in patients with epidermodisplazie veruciforma.
Warts are spread all over the world. Although the frequency is unknown are estimated to affect 7-12% of the population. Frequency is increased among immunosuppressed patients and those who work with meat. Common warts are asymptomatic, but can cause cosmetic disfigurement and tenderness. Plantar warts can be painful and extensive damage can impede the plant. Nongenitale warts malignant changes are rare but have been reported, warts carcinoma. It is considered to be a slowly evolving squamous cell carcinoma, locally invasive, well differentiated, which can easily be confused with a simple wart. It can appear anywhere on the skin surface but is more frequently planted. While this type of cancer rarely metastasize may be locally destructive.
There are many ways to treat warts, but none is uniformly effective. The method starts with the least expensive and painful. It will keep invasive and expensive procedures for refractory extensive warts. Immunosuppressed persons are usually refractory to treatment. Use topical agents such as salicylic acid solution is first adopted. Intralesional injections, systemic agents, hyperthermia, adezioterapia, vaccines, Cryosurgery with liquid nitrogen, curettage and laser electrodesicarea with multiple and large reserved for warts. Approximately 65% of warts disappear spontaneously within two years. When warts resolve spontaneously no scar remains. However scarring can occur as a result of different treatment method.
Pathogenesis and causes of warts Warts can affect any area of the body and mucous membranes. Infection is limited to the epithelium and cause systemic dissemination of the virus. Replication appears in the epithelial cells differentiated from upper level of epidermuli, however, viral particles have been described in the basal layer. Warts are caused by HPV, a virus that is double stranded, circular DNA with capsid icosahedrica. They were discovered more than 100 types of this virus: -Common warts are caused by types 2 and 4, then 1, 3, 27, 29, 57 Deep-mimecia palmoplantare-warts-types 1, then 2, 3, 4, 27, 29, 57 Flat warts-types-3, 10, 28 Butcher-type 7-warts Focal epithelial hyperplasia, Heck disease-types-13, 32 Cystic-type 60-warts.
Wart transmission risk factors include: Skin-trauma and maceration Work-environment of the hands wet Hyperhidrosis-feet Swimming-pools, manicures -Individuals who handle raw meat.