Saturday, January 29, 2011

Chondrosarcoma Treatment

Chondrosarcoma

    
* Introduction
    
* Diagnosis
    
* Treatment 

Chondrosarcoma Treatment 
Treatment
Extended surgical curettage and bone graft or artificial plastic. Skeletally immature patients is recommended to fill the bone defect with polymethylmethacrylate, this skeletal growth while allowing the tumor cells are destroyed. In older patients where skeletal development is not a problem bone grafting is recommended for small lesions. For large lesions and cement reconstruction is necessary. Filling the defect with polymethylmethacrylate is recommended after removal of recurrent lesions.
Block or wide excision is reserved for advanced tumors that can not be treated by intralesional excision. The rate of recurrence after en bloc excision is 7%. Options include reconstruction after wide excision and reconstruction with structural allogrefarea endoprosthesis or allograft prosthetic.
Chondrosarcoma Treatment
Prognosis: The prognosis is generally correlated with lesion size, anatomical location and histological grading of the site. Patients with axial lesions were most negative prognosis from those with lesions of the appendicular skeleton. 5-year survival rate for patients with grade 1 lesions is 90%, the rate dropped to 29% for those with grade 3 tumors. Grade 1 lesions do not metastasize. Metastatic extension typically is most frequently associated pulmonary lesions of grade 3. Extending through the lymph nodes is more frequent in chondrosarcoma than in other bone neoplasms. Tumor Recurrence after surgery occurs in 5-10 years. Recurrent chondrosarcoma is more aggressive than the primary, and the histological grading is increased.

1 comment:

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