Saturday, January 29, 2011

Chondrosarcoma Diagnosis

Chondrosarcoma

    
* Introduction
    
* Diagnosis
    
* Treatment

Diagnosis
Studi imaging: Radiograph is essential for initial diagnosis of chondrosarcoma. Radiograph is sometimes supplemented with CT scan, which is more sensitive in detecting calcifications in the matrix and confirm intramedullary tumors endostiale cortical damage. Radiography typically shows a lesion radiolucenta, which often contains calcifications matrix. The degree of organization may be correlated with tumor grade matrix calcification. Aggressive tumors contain irregular calcifications. Typical appearance of rings and arcs. Intramedullary lesion edge is determined by the degree of tumor aggression. It is bad defined. The presence of cortical destruction and a soft tissue mass indicates malignancy.
Radionuclide scan showed increased intake of radioisotopes in areas of bone scans, but the difference between chondrosarcoma and encondrom not argue. Capturing the isotope can show metabolic activity osteocondrom or malignant transformation. In the absence of malignancy is unusual capture.
Magnetic resonance imaging is the preferred method for evaluating tumor extension extraosoase intramedullary extension and demonstration. MRI is useful in evaluating the thinning carticajului osteocondrom meet to develop a secondary chondrosarcoma. It is the most sensitive for identifying small amounts of calcified matrix intro tumor.
Chondrosarcoma Diagnosis
Histological examination: macroscopic Chondrosarcoma looks gray-white lobe. May show focal calcification, mucoid degeneration or necrosis. It is differentiated from benign cartilaginous lesions by large nuclei, multiple cells in gaps, binucleate cells and nuclei pleomorfismul hyperchrome. The differential diagnosis is made with the following conditions: myocardial bone encondromul, osteosarcoma, osteocondromul, fibrosarcoma.

1 comment:

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