Oral Candidiasis
Treatment
The fund will treat diseases that favors candida, will discontinue or reduce the doses of antibiotics, corticosteroids, if probable cause is. In patients with severe immunosuppression therapy for prevention of colonization is extensive. Patients at high risk of candidiasis, such as those with HIV and people receiving chemotherapy for cancer, immunosuppressive or antifungal prophylactic antibiotics requires time. Topical agents in HIV infections in general infection control until the immune deficit requires increasing systemic agents. Topical antifungal agents are available as tablets, creams and solutions. Oral solutions are effective for people with dry lining or may not dissolve the tablets.
Dentures often contain candidate. To prevent denture-induced stomatitis solutions are needed for the mouth. They contain lithic and proteolytic enzymes, benzoic acid, which completely destroys candidate. Solutions can be divided into gurpe mouth depending on the components contained: alkaline peroxides, alkaline hypochlorites, acids, disinfectants and enzymes. Most effective are the enzymes. Benzoic acid and chlorhexidine gluconate completely destroy candida.
Antifungal therapy
Fluconazole is active against oral candidiasis in HIV and produce remission intro week. It is preferred because it has serious side effects and is rapidly effective. Maintenance therapy with fluconazole is required to prevent relapse. Other antifungal agents available include: cotrimazol, miconazole, econazole, ketoconazole, fluconazole, itraconazole, which are synthetic antifungal activity spectrum against a large number of fungi including Candida. It works by inhibiting ergosterol biosynthesis, the major fungal membrane sterol. A side effect of azoles is the accumulation of ergosterol precursors. Triazoles and diazoli is important for hepatotoxicity and endocrine toxicity. Resistance to azoles is well known today and become significant, especially in people with HIV. Patients should avoid smoking, xerostomia medications, antibiotics, corticosteroids and imunosupresantele.
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