Heterotopic ossification - ectopic (myositis ossificans) - Signs and symptoms

Heterotopic ossification can be divided into three types:
Myositis ossificans progressive (fibrodisplazia ossificans progressive)This disorder is one of the rarest genetic disorder. Transmission is autosomal dominant variable expression vu. The condition is characterized by recurrent swelling, painful soft tissue leading to progressive ossification and congenital malformations of the big toe. There is no cure for this form of heterotopic ossification. They reported little benefit from the use of corticosteroids and etidronic.Most patients die early with restrictive lung disease and pneumonia.
Patients appear normal at birth, except characteristic malformation of the big toe. Episodic develop painful swelling of soft tissues in the first 10 years of life. Although some exacerbations regress spontaneously, most soft connective tissue turn into mature bone.Minor trauma (muscle fatigue, dental extractions, intramuscular immunizations, contusion) or viral infections cause exacerbations painful progressive ossification. Most patients are immobilized and in the third decade of life care needs for daily activities.
Ossification following embryo model of bone growth. It is observed first in the dorsal region, axial, cranial and proximal body and later in ventral regions, appendices, and distal tail. A few skeletal muscles, including diaphragm, tongue and extraocularii are avoided, with heart and muscles metezi.
Traumatic myositis ossificans:This condition develops painful areas in muscles or soft tissue only after a local trauma, a muscle tear or repeated minor trauma. Mass progressively painful area with cartilaginous consistency in 4-7 weeks is palpeaza a solid mass of bone. Common localizations include pectoralis big biceps and thigh muscles.Traumatic ossification occurs in 20% of patients prone. After total hip arthroplasty and acetabular fracture surgery, the incidence is 2-63%. The disease seems to complicate nonoperative treatment of acetabular fractures. Hip arthroplasty with cement after the incidence is 8-90%, although many cases are asymptomatic. For fractures of the distal humerus and proximal humerus arthroplasty incidence is 10-90%.
After arthroplasty, heterotopic ossification may be a condition with physical symptoms, pain and stiffness, or may be asymptomatic and detected radiologically. If symptomatic ossification is present, the affected joint loses mobility, with painful swelling.
Neurogenic heterotopic ossification:This condition is still an unknown disease. Approximately 10-35% of patients with heterotopic ossification shows significant reduction in the movements of the affected joints. These shows joints ankylosed. The condition is found in patients with brain and spinal cord injuries with damage to the shoulder, elbow, knee.Ossification related to brain injury or spinal meduvei not regress and cause pain and immobilization of the affected joints with complete ankylosis and severe disability. Among patients with neurological deficits, 10% had severe functional limitations with heterotopic ossification. Extension injury is associated with negative prognosis for recovery of patients with brain lesions. In patients with spinal cord injuries, large fossil ossification leading to inability to puncture the skin and orthostatic position of the column.