Haemophilia type A - Diagnosis

Positive diagnosis:

For diagnosis of hemophilia issue correlate clinical and laboratorydata.
Clinical symptoms include: bleeding exteriorized, incoercible,deep hemorrhage (tissue, hollow, visceral) sometimes extensive.

Laboratory tests efctuate highlights: bleeding time (TS) normalclotting time (CT) increased by performing the test in the test tube,Howell, they are screening tests. It also highlights the prothrombinconsumption low, normal is between 40-50 seconds. PTTK PTTand factor VIII increase when less than 20%. Thromboplastingeneration test is altered during Quick (TQ), TS, thromboplastin,fibrinolytic activation is normal.
During two of the coagulation cascade, prothrombin conversion tothrombin by the action of thromboplastin time is explored Quick(TQ), it is normal for the thromboplastin is added from outside.
The first stage of coagulation, intrinsic and extrinsictromboplastinoformarea by the PTT and PTTK is explored.
Tests of blood clotting time correction (TC) when fresh plasma issuggestive highlights with haemophilia A or factor Adsorbedplasma, suggestive of hemophilia B. Factor

Differential Diagnosis:

Differential diagnosis is made: deficiency of factor IX, XII;syndromes parahemofilice
deficient in factors V and VII, immune thrombocytopenic purpura(ITP).