Circumscribed Angiokeratom

Circumscribed AngiokeratomAngiokeratomul comprises a group of vascular ectazii involving the papillary dermis and cause papillomatosis, and hyperkeratosis avantoza epidermis. There are several clinical variants of the disease: circumscribed angiokeratomul is a guy with angiokeratomul Mibelli fingers, events that include the neck, trunk. These lesions are clinically important because clinically mimicking malignant melanoma.
In many cases the lesions are present at birth but can occur in childhood or adolescence. Is associated with circumscribed Angiokeratomul angiokeratomul the scrotum and Fordyce's spots-angiokeratomul caviar tongue. Other clinical associations are those with Cobb syndrome, Klippel-Trenauanay syndrome, cavernous hemangiomele, hemangieactica hypertrophy, angiokeratomul corporis diffusum and arteriovenous fistulas of traumatic.Angiokeratomul is a benign vascular swelling involving the papillary dermis. It shows mortality. Because vascular disease is a cause recurrent bleeding. It is found mostly on the lower extremities as asymptomatic solitary papule or plaque, but also the upper extremities and trunk. Fordyce Angiokeratomul crotului is characterized by papules of 2-5 mm, blue-red, scaly surface located on the scrotum, sheath penicului, labia majora or lower abdomen.
Medical treatment of these lesions is not always necessary. Surgical therapy may be necessary for cosmetic reasons or because of the possibility of melanoma. The practice of ablation or excision of lesions.
Pathogenesis and causes
Are not true angiomas Angiokeratoamele rather teleangiectazii preexisting vessels. Circumscribed angiokeratoamelor development mechanism is unknown. Several causative factors are incriminated as the development of congenital, pregnancy, trauma, subcutaneous hematomas and tissue asphyxia.It is considered a risk factor contributing to increased venous pressure and training. In describing the variant angiokeratomului Fordyce and varicocele or other conditions of increased venous pressure: hernias, epididymal tumors, bladder tumors. Vulvar Angiokeratoamele contain a predisposing factor in 54% of cases, pregnancy, postpartum, varicose, total hysterectomy. Angiokeratoamele vulcare penis and have been reported after radiotherapy for genitourinary tumors. Fordyce's Angiokeratomul is associated with Nevus lipomatos, oral mucosa and xantomul angiokeratoamele papular.
Signs and symptoms
Circumscribed AngiokeratomulAngiokeratomul can be inherited or earned. Lesions are present at birth but develop in childhood and adolescence. Angiokeratomului circumscribed lesions on the lower extremities are described as solitary asymptomatic papules or plaques, but can be found on the upper extremities and trunk. Occasionally, multiple lesions develop after adolescence. Patients may notice darkening of the lesion or other modifications. Sometimes they may be worried about the neoplastic nature of the lesion suggesting a melanoma.Angiokeratomului compressible lesions consisting of papules, black or red, warty and supradenivelate. It can be seen and small nodules and plaques. Some develop a tape distribution of lesions. On the surface lies a scaling hyperkeratotic lesions. Lesions were associated with irregular borders and pigmentation attributed to intraepidermal hemorrhage or hemosiderin storage in the dermis. If you are injured may excoriate or erosion and bleeding.
Fordyce AngiokeratomulThe patient shows the evolving history of papules on the scrotum for several years. He may not realize the damage, noticed only when they singereaza. There are sexually transmitted and non-malignant. Singereaza vulvar lesions spontaneously during pregnancy or intercourse. Most lesions are asymptomatic, shows little pain or itching.It is characterized by papules of 2-5 mm, dome, blue or red, with scales on the surface. Patients younger shows small lesions, less erythematous and hyperkeratotic, from which most older shows dark scales and lesions. The lesions are present on the scrotum, labia large penis sheath and lower abdomen.
Diagnosis
Histological examination. Numerous thin-walled dilated vessels are positioned in the superficial papillary dermis or submucosa, having a close relationship with the parakeratoza acantotic epidermis. Epithelium is hyperkeratotic. Vessel thrombosis is common, with recanalization or occlusal space, forming specific endothelial hyperplasia. Underlying skin tissue is not involved but may contain siderofage.The differential diagnosis is made with the following conditions: angiokeratomul corporis diffusum, in cherry hemangioma, melanoma, maduza bites, Osler-Weber-Rendu syndrome, genital warts.
Treatment
Therapy is not mandatorie in this condition. Cosmetic reasons may try various methods of surgical removal of lesions. Excision is indicated only if there is a single lesion, is performed under local anesthesia and carries a good cosmetic result. Cryotherapy by liquid nitrogen application is used for resolution of lesions but residual hypopigmentation and scarring. Electrocautery can be used with or without local anesthesia and causes beneficial results. Argon laser or copper shows good results with minimal scarring. Recurrence after surgical excision or ablation lesions exist. Since angiokeratoamele pharmacological therapy are benign vascular lesions do not apply. Spontaneous resolution has not been reported. Lesions will persist if not treated. Patients with multiple lesions are more prone to recurring after treatment compared to those with solitary lesions.