Studi imaging:
Radiograph is essential for initial diagnosis of chondrosarcoma.Radiograph is sometimes supplemented with CT scan, which ismore sensitive in detecting calcifications in the matrix and confirmintramedullary tumors endostiale cortical damage.
Radiography typically shows a lesion radiolucenta, which often contains calcifications matrix. The degree of organization may becorrelated with tumor grade matrix calcification. Aggressive tumorscontain irregular calcifications. Typical appearance of rings and arcs.
Intramedullary lesion edge is determined by the degree of tumoraggression. It is bad defined. The presence of cortical destructionand a soft tissue mass indicates malignancy.
Radionuclide scan showed increased intake of radioisotopes inareas of bone scans, but the difference between chondrosarcomaand encondrom not argue. Capturing the isotope can showmetabolic activity osteocondrom or malignant transformation. In the absence of malignancy is unusual capture.
Magnetic resonance imaging is the preferred method forevaluating tumor extension extraosoase intramedullary extensionand demonstration. MRI is useful in evaluating the thinningcarticajului osteocondrom meet to develop a secondarychondrosarcoma. It is the most sensitive for identifying smallamounts of calcified matrix intro tumor.
Histological examination: macroscopic Chondrosarcoma looksgray-white lobe. May show focal calcification, mucoiddegeneration or necrosis. It is differentiated from benigncartilaginous lesions by large nuclei, multiple cells in gaps,binucleate cells and nuclei pleomorfismul hyperchrome.
The differential diagnosis is made with the following conditions:myocardial bone encondromul, osteosarcoma, osteocondromul,fibrosarcoma.
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