Nevus sebaceous

Nevus sebaceous

    * Introduction
    * Signs and Diagnosis
    * Treatment
Hamartoasa sebaceous nevus is a circumscribed lesion composed predominantly of sebaceous glands. Sebacate and warty epidermal nevi nevi are considered by many doctors as variants. Medical importance alone is associated with nevus sebaceous description of benign and malignant changes in some cases. Malignant transformation occurs in 10-15% of injuries although recent studies suggest that this rate is lower. These neoplasms usually occur during adolescence and adulthood. Changes rarely occur in childhood, under 5 years old.
The most common malignant cancer that develops in the basal cell damage is carciomul. Recent studies show that the development of basal cell carcinoma or any other malignant neoplasm is very rare. The most common benign tumor is trichoblastomul. Other benign and malignant tumors include siringochistadenomul papiliferum, keratoacanthoma, cystadenoma, apocrine cystadenoma, leiomyoma, sebaceous cell carcinoma.
The risk of malignancy is difficult to determine accurately and malignant changes can occur at any age. Because of this risk many authors recommend complete surgical excision before puberty is tough because the injury and the risk of malignancy increases with age.
Pathogenesis
Postzigotice somatic mutations can cause many clinical expressions of mosaicism. Pluripotent cells can give rise to mutations hamartoamelor multiple cell lines.
Familial cases have been reported. Mutations in pluripotent cells during embryogenesis may generate different lines including the nevi organoizi deferentiere. Nevus sebaceous seems to respond to hormonal influence. Lesion may be high at birth, childhood and payment becomes prominent again during puberty.