Bowen disease Symptoms and Diagnosis

Bowen disease
Symptoms and Diagnosis
Bowen's disease has a high incidence in the elderly. Asymptomatic patients have a spot, slowly progressive erythematous with scaling. It can occur anywhere on the mucocutaneous surface. It shows that a single lesion or multiple. It can occur on sun-exposed areas covered. Head and neck are the most common areas affected, followed by States. Lesions vary in size from several mm to cm. is this a well-demarcated border, irregular. The lesions are erythematous, with scales, or plates may become hyperkeratotic, scaly, cracking or ulceration. Pigmented lesions are rare, especially in the genital area and nails. These lesions can simulate melanoma. Bowen's disease can occur on mucous areas.
Penis form of the disease. Mean age of onset is 51 years. Characteristic lesions are solitary or multiple erythematous boards. Texture can be smooth, velvety, scaly or warty. Always affects the glans penis or adjacent mucosal surfaces, or both. The lesions may represent forms of carcinoma in situ induced by papilloma virus. Representative Symptoms include: -Erythema, crustificare, desquamation, ulceration -Bleeding, pain, itching, dysuria -Debacluri penis, difficulty in decalotare.
Bowen disease Symptoms and Diagnosis
Laboratory studies: By tangential shaving skin-biopsy or fine needle puncture to confirm the diagnosis -Culture bacterial, fungal, Tzanck test, examination with potassium hydroxide, Gram stain, the shape penis.
Bowen disease Symptoms and Diagnosis Histological examination. Bowen's disease is an anaplastic the entire thickness of the epidermis, with loss of normal maturation of its components. Keratinocytes are atypical and in disarray, described as blown by the wind. Basal layer is intact. Vacuolation are present in epidermis, mitoses, individual keratinized cells, multinucleated cells. Superficial dermis shows a moderate degree of infiltrating lymphoma. The differential diagnosis is made with the following conditions: Balan xerotica Peripheral, balanopostita, mucosal candidiasis, contact dermatitis, bullous diseases induced by drugs, boards psoriasis, actinic keratosis, basal cell carcinoma, lichen simplex cronicus, Paget's disease, tinea corporis.