Ankylosing Spondylitis

Ankylosing Spondylitis

    * Introduction
    * Pathogenesis
    * Causes
    * Signs and symptoms
    * Evolution and prognosis
    * Treatment
Ankylosing spondylitis is a chronic inflammatory disease, of unknown cause that primarily affects the spine. It can also affect other parts of the body frame such as shoulders, thighs and knees, and tendons and ligaments around the bones and joints.
The disease begins around the second and third decades of life, the prevalence was three times higher in men than in women.
It is also known as Marie-Strumpell disease or Bechterew disease.
There is no known cause of this disease, but is believed to be caused by a combination of certain environmental factors, genetic risks and the immune system. Researchers have identified a number of risk factors that increase a person's chance of developing this disease. They are known as risk factors for ankylosing anchilopoetice.Prezenta that person does not guarantee that they will only increase the risk of disease to develop. They are: -This disease to other family members -Male -Presence of genetic factors Young-age Good historical and certain infections.
The disease is characterized by back pain and morning stiffness, these symptoms typically occur in adolescents or young adults. Are highly variable from one person to another and not all patients will have severe symptoms or spinal fusion. May be affected and other body parts including eyes, heart, lungs and digestive tract.
Before diagnosis, it is necessary to make differential diagnosis with other similar diseases such as: Rheumatoid-arthritis Psoriatic-arthritis -Reactive arthritis -Osteoporosis Bone-degenerative diseases -Other causes of back pain.
Some therapies include ankylosing spondylitis: Life-style changes -Medication -Surgery -Continuous monitoring.
Spondyloarthropathies are a group of diseases that can cause inflammation of joints throughout the body, especially the spinal cord. They are characterized by negative rheumatic factor and HIA-B27 is positive. Apart from ankylosing spondylitis, this group includes: -Reactive arthritis Psoriatic-arthritis Enteropathy-arthritis (Crohn's disease, ulcerative colitis).