Bowen disease
Treatment
Medical therapy. Topical administration of 5-fluorouracil under occlusion, followed by a keratolytic or cryosurgery is an effective regime in Bowen's disease. 5% imiquimod cream, a topical immune response modifier seems to be a successful treatment for Bowen's disease with multiple locations. Photodynamic therapy shows promising results in treating superficial carcinomas. It involves introducing a photosensitizing agent in the body, preferentially retained by the tumor. Then the affected area is exposed to blue light to the active agent, causes the release of toxins and destroy the tumor.
Surgical therapy. Simple excision with conventional margins. It is the technique used for small lesions that are not problematic areas: the face and fingers. Although the lesions are well demarcated, the current expansion of clinical disease can be ejected, so excision must provide safety margins of 4 mm.
Bowen disease Treatment Mohs micrographic surgery. It is an excellent method for large lesions, recurring or from areas where the tissue is important. Use systematic surgical removal of cancer tissue with small mergini safety and frozen sectioned for examination. Safety margins are 100% negative for carcinoma.
Electrodesicarea and curettage, cryotherapy and laser ablation of carbon. These surgical methods are blind, without pathological confirmation of the removal of carcinoma.
Bowen disease Treatment Prognosis. The prognosis is excellent for all forms of disease. Cure rate is 90%
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