Skin Manifestations of smoking

Skin Manifestations of smokingCigarette smoking is number one cause of preventable death. Represents an addict usually associated closely with severe internal diseases like cancer, pulmonary disease and cardiovascular disease. Smoking has manifesatri and external skin.
Poor wound healing.Smoking is criminalized for wound healing TROUBLE, in particular the surgical and grafting. Determining mechanism is multifactorial. Sin nicotine cigarettes cause vasoconstriction in cutaneous vessels decreased tissue oxygenation. Smoking increases carboxihemoglobina, platelet aggregation, blood viscosity, reduced storage and decreases collagen formation of prostacyclin, with negative effects on wound healing. In addition to vasoconstriction associated with smoking is not a transient phenomenon. Smoking a single cigarette can cause cutaneous vasoconstriction for 90 minutes while a full day package cause hypoxia.
Wrinkles.The danger many smokers face wrinkle is a stronger reason than that of pulmonary cancer or other life-threatening disease to quit smoking. Studies indicate that women who smoke have a much more wrinkled skin, wrinkles is early, skin color is dark yellow or gray tint.The precise mechanism by which smoking cause wrinkles is poorly understood. Elastin in the skin of non-smokers exposed to sunlight is more fragmented and thick compared to the non-smokers. Chronic ischemia of the dermis is a predisposing factor. Decreased collagen synthesis in chronic ischemia may be a factor. Prooxidant effects of smoking may contribute to premature wrinkling of the face.
Hidrosadenita suppurativa.Although the mechanism is unknown, studies show that smoking contributes to hidrosadenita suppurativa by altering neutrophil function, impaired function of sweat glands, sweat excretion of compounds in tobacco and poor wound healing promotion.
Palmoplantara pustular.Some studies show close "Association of this disease and smoking. Smokers have a risk of July. 2 times more likely to develop the disease compared to nonsmokers. Unfortunately, smoking cessation is not always translate to the clinical improvement palmoplantare pustulosis.
Psoriasis.Numerous studies show the connection between smoking and psoriasis. They show a high incidence of psoriasis among smokers but the connection between smoking and psoriasis is not known.
Scuamo cell skin cancer.Some studies show that smokers are at increased risk of squamous cell cancer compared with nonsmokers. The risk increases with the number of packs smoked per day and duration of habit. Mechanisms are immunosuppressed due to the effects of cigarette smoke.
Melanoma.Although there is evidence that smoking was associated with an increased risk of melanoma, several studies show that when are compared with nonsmokers, smokers are more likely to have metastases at first presentation have a low survival rate after diagnosis, shows and visceral metastases are prone to dying from melanoma. Smokers have a negative prognosis for melanoma due to adverse effects of smoking on the immune system, including a diminished capacity to mount an immune response to melanoma tumors transplanted.
Anogenital cancer.Several studies associate smoking with anogenital cancers (vulvar, anal, penile, vaginal, cervical). Of these five areas, three are most common: vulva, anus, penis.
Oral lesions.Many oral lesions, including lip cancer are significantly more common in smokers. Smoking is a risk factor for lip cancer, combined with excessive sun exposure, the two are synergistic. Oral cancer is linked to smoking, and associated with alcohol consumption, the risk is even higher.
Leucoplakia occurs more often in smokers, while a small percentage of patients suffering malignant transformation leucoplakie. Palace leucokeratoza nicotine smoker or exclusive palaces is seen in smokers, especially in the pipe. Represents a uniform keratosis hard palate with multiple red papules which translate nipples swollen salivary glands. Language smoker nicotine leucoplakia gloss or a similar phenomenon is observed on the back of the tongue.Gingivitis is characterized by acute necrotizing ulcerative lesions of interdental papillae associated with pain, bleeding and a fetid odor of the mouth. Exclusive smokers and appears to correlate with the amount of cigarettes smoked per day.
Nutrition.Apart from nutritional deficiencies may occur in these patients smoking has some effect on nutritional status. It was demonstrated that low levels of vitamin C in smokers. Hypovitaminosis severe risk is increased in smokers, especially those who did not supplement. Skin manifestations of vitamin C deficiency include skin hyperkeratosis, and hemorrhages perifoliculare of closed spaces, gingival hypertrophy, poor wound healing.
Acne and oral thrush.It seems that smoking has a protective effect on the appearance of acne sia afetelor mouth. It is thought that nicotine has an anti-inflammatory effect against acne.
Other skin lesions.Burger's disease (Peripheral tromboangeita) featuring skin lesions: erythema, ulceration, necrosis is closely associated with smoking. Yellow and brown stains on fingers and nails are a sign of smoking. Mustache smoker smoker is analogous to fingernails. There is a brown or yellow discoloration on the distal hair mustache mustache gray or white until the hardcore smokers.Smoking is a risk factor in the development of discoid lupus erythematosus.
Nicotinic therapyNicotine is a pharmacologically active substance, and in some patients this activity has a beneficial effect as treatment. The reported benefits of nicotine therapy for pyoderma gangrenosum, pemphigus vulgaris.Recognizing dermatologic effects of tobacco consumption may be a key element in the diagnosis of internal diseases associated with smoking. For many smokers the most visible and rapid effect of this drug as yellow teeth, wrinkles and bad breath odor are more persuasive incentives for smoking cessation than the knowledge that smoking kills.