Fibrosarcoma - Diagnosis

Imaging Studies:Plain radiograph of the affected anatomical area is needed to assess primary or secondary damage to the bone. Typically there is a noticeable aspect Destruction osteolytic area of ​​permeation.Periostiala weak reaction or reactive sclerosis is present. To assist in the diagnostic X-ray bone lesions and determine the location, size and extent of local. For soft tissue masses can be estimated size and bone damage.CT scan for bone fibrosarcoamele is used to determine bone involvement, bone destruction or reaction. Fibrosarcoamelor density is similar to surrounding normal muscle. Signs of the fracture or impending fracture can be observed, and the tumor can be located easily. Chest CT scan is indicated to detect metastasis.MRI is the best way to examine the soft tissue mass extending into and extraosoase detection for many bone sarcomas. It is useful to bring information about local extension, tumor size and involvement of neurovascular structures. Fibrosarcoma of bone is usually an extension extraosoasa.Technetium 99 bone scintigraphy is useful in evaluating tumor stage, detecting bone metastases or polyostotic disease. For fibrosarcomas technique has been replaced by MRI.Bone biopsy is the most important test for the diagnosis. Biopsy is the first step in treatment.
Histological examination:The tumor may present different degrees of differentiation: differentiated-low grade, intermediate and high-anaplastic neoplasia. Depending on the differentiation of tumor cells may be similar to mature fibroblasts, secrete collagen, with rare mitoses.These cells are arranged in short bundles divide and come together, giving the appearance of fish bones. Poorly differentiated tumors are composed of atypical cells, pleomorfe, giant, multinucleated, with numerous atypical mjitoze and reduced production of collagen. This immature blood vessels without endothelium favors-sarcomatous marrow metastasis.
The differential diagnosis is made with the following diseases: fibrous dysplasia, fibrous histiocitomul, osteosarcoma, Paget's sarcoma, malignant neurosarcom, rabdmiosarcomul, hemangioma, vascular haemarthrosis, lymphangioma, miofibromatoza, teratoma.