Xantom veruciform

Xantom veruciform Xantomul veruciform is unusual lesion that usually occurs on the oral mucosa around the middle or the scrotum to the elderly. The most frequent location of oral mucosa is veruciform xantomului. Lesions may occur on the scrotum, perineum, or skin prone to factors such as lymphedema or epidermal nevus. The most common lesions veruciform issue, but may be polypoid, or sessile papilamathosis. Rare lesions were described as cysts. Veruciform xantomului feature is the presence of a large number of buds histiocite sparkling limited to connective tissue damage.
Patients presenting with asymptomatic skin or mucous membrane lesions. The lesions may be similar to warts, polyps or hyperkeratotic lichen, gray or red. They are usually sessile lesions. Although it may be affected by any area of the oral mucosa are the most common gum disease. Xantomului warts is unknown aetiology. It is considered a reactive process than a true neoplasm. Etiological factors are incriminated. Treatment of choice is local surgical excision is always curative. Recurrence is rare and can be treated with appropriate secondary excision. The prognosis is excellent.
Petogenie and causes
Veruciform xantomului Pathogenesis is unknown. Many authors consider to be a reactive process than a true neomplasm. Squamous cell damage with increased epithelial cell turnover, leading to epithelial cell storage of waste that are ingested by macrophages in the corium may lead to the development of this injury. It was proposed and an immunological etiology, association with human papilloma virus.
Signs and symptoms
Most cases occur in people of middle age, the injury is rare in children. Patients usually present with a history of sensitive or asymptomatic lesion on the skin or mucosa. Veruciform xantomului clinical appearance is not diagnostic, the diagnosis is always made on histopathological examination. Depending on the nature of the lesion xantomul veruciform may be warty, papillary or lichenoid, especially those who are and hyperkeratotic lesions. Lesion is often misdiagnosed as a papilloma.
The lesion may appear as a papillary process, warts or flat lichenoid diameter between 0. 2-2 cm. Depending on the degree of keratinization xantomul may be gray or red. The process can be sessile but usually pedunculate. Any area of the mouth may be affected, particularly the gums and alveolar edge. Because of slight trauma preferences has been proposed to play a role in etiopathogenesis. Lesions appear on oral mucosa and the scrotum are not associated with any predisposing factor. Lesions appear on the legs are associated with lymphedema. Outside the perineal skin lesions are associated with other processes: epidermal nevi, congenital hemidisplazia, ihtioziforma erythroderma, severe sun damage, dermatitis, chronic eczema, recessive dystrophic epidermolysis bullosa and discoid lupus erythematosus.
Diagnosis
Histological examination. It describes a varied degree parakeratoza without epithelial cell atypia, the lesion is exofitica dermis without extension. Characteristic element is the presence of large foamy cells in the connective tissue papillae. These cells filled the entire papilla but rarely extend outside papilla base. These cells are macrophages. Foaming material is formed from cholesterol, cholesterol esters. Underlying lesion may be seen in discrete inflammatory infiltrate. Microorganisms are not present. The differential diagnosis is made with the following conditions:'s eritroplazia Queyrat, seborrheic keratoses, squamous cell carcinoma, carcinoma warts, genital warts, oral papillomas.
Treatment The treatment is local surgical excision of the lesion. The prognosis is excellent. Recurrence is rare.