Chemotherapy is recommended in various combinations andarrangements. Treatment lasts 6-9 months and require tworegimens, the first with vincristine, doxorubicin and cyclophosphamide, and etoposide and ifosfamide in second with.Control of primary tumor is critical for patient prognosis. They wantdefinitive surgical margins. Surgical techniques must be made depending on tumor location and size.
Reassessment is done every 5-6 years after completion oftherapy. Late side effects of chemotherapy requires evaluation.Recurrence of the primary tumor is the first increase in 10 yearsafter diagnosis. Secondary cancers occur in about 2% of patientsafter 5 years after diagnosis. The most common malignancy isacute myelogenous leukemia. Therapeutic toxicity on the heart andkidneys must be monitored. In general, chemotherapy cause hair loss, nausea and vomiting, diarrhea.
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