Gastric and duodenal ulcer

Gastric and duodenal ulcer

    * Introduction
    * Clinical manifestations and diagnosis
    * Treatment
Peptic ulcer is an erosion of the lining of the digestive In a segment that penetrates muscle lining, it is typical to die or develop stomach ulcers are due to duodenal.Aproape all Helicobacter pylori infection or NSAID administration. Symptoms include epigastric burning, and pain that gives to food. Ulcers may have a diameter from several mm to cm, can occur at any age, even children, but are more frequent at the age of two. Uema some years it was believed that stress or spicy foods would lead to peptic ulcers, is now shown that consumption of NSAIDs and H. pylori infection because they really are. The risk of developing peptic ulcer is increased in the following conditions: -Age-is often over 60 years Sex-is-especially in women -Use of corticosteroids and NSAIDs together Medical history of ulcer-positive. Complications that can occur are: Lower-or upper gastrointestinal bleeding -Perforation -Gastric or duodenal obstruction. Treatment includes the use of antacid therapy: proton pump inhibitors, H2 antihistamines, gastric protectors, and antibiotic therapy to eradicate H. pylori infection.
Causes and pathogenesis H. pylori infection and prolonged use of NSAIDs alters mucosal barrier protection by making it to acid.H.pylori succeptibila is present in 50-70% of patients with gastric ulcer and 30-50% in those with ulcers duodenal.Daca it should be eradicated, only 10% of patients will suffer recurrent disease, compared with 70% in the absence of antibiotic treatment. NSAIDs are crucial in more than 50% of ulcers. Smoking is also a risk factor, it reduces the power of healing and increase the incidence recurentelor.Riscul is correlated with the number of cigarettes smoked per zi.Desi alcohol is a promoter of acid secretion, yet no data on its involvement in the etiology. Very few patients with Zollinger-Ellison syndrome, gastrin hypersecretion. Although stress is a causative factor of peptic ulcer, it worsens the symptoms and in some cases delayed healing.