Wednesday, June 15, 2011

Jaundice and pregnancy

Liver functions are disturbed during pregnancy. Progesterone, present in large amounts, causes smooth muscles throughout inertia and consequently in the gallbladder with subsequent stasis. Therefore there is a biliary retention, bile is viscous and bile salts present in urine and bilirubin. These are not pathological in pregnancy, bilirubin remained within normal parameters in normal pregnancy. There are two main types of jaundice:- Pregnancy-related jaundice;- Independent jaundice of pregnancy.
Pregnancy-related jaundice
 
One of the most common pregnancy-related jaundice cholestatic jaundice is benign (recurrent jaundice of pregnancy). It appears in the third quarter of pregnancy and bile stasis due to increased amounts of bile and a viscous consistency.
 
Signs and symptoms - clinical picture is characterized by itching (which is the characteristic mark early), dark urine, discolored stool.
 
Diagnosis - samples of liver, cholesterol is moderately increased serum transaminases and phosphatases are normal, and disproteinemie tests are negative. Foasfataza alkalinity is high.
 
Breast prognosis is good. Fetal prognosis is reserved, the fetus may be born prematurely are at risk of fetal death in utero, but the load can reach term.
 
Other pregnancy-related jaundice are:- Jaundice occurring toxic substances through ingestion of abortifacients;- Jaundice postanestezice - after prolonged anesthesia;- Jaundice in early disgravidiile- Jaundice by prolonged treatment with chlorpromazine- Hemolytic jaundice during toxico-septic abortion;- Disgravidiei of jaundice in the primtrimestru incoercible vomiting, accompanied by azotemia;- Jaundice occurring in pilonefrita gravido-toxic.
 
Jaundice independent task
 
Familial hemolytic jaundice may worsen during pregnancy. Other independent jaundice of pregnancy are those with biliary obstruction. They are very rare and are due to a preexisting gallbladder lithiasis pregnancy.
Such medical treatment is only jaundice. Surgery is indicated only if the gallbladder or gangrene piocolecist appears suprainfecteaza and gallbladder surgery is done interevntia independent of gestational age. In other cases, surgery is contraindicated because it causes abortion or premature birth.
 
Jaundice occurring during viral hepatitis is quite common. They may be forms of hepatitis A (epidemic occurring in the middle) or hepatitis B or C forms of which occur mostly after transfusion or by injection. Viral hepatitis may have a short form, 20 days, or an extended form of chronic risk. There may be serious forms which may come to hepatic coma and death. In these cases indicates therapeutic abortion. Other forms of manifest and serious mental disorders, which are first; hepatitis is diagnosed by tests in these cases and the increasing importance floculatie transaminases.
 
Breast prognosis is good. Fetal prognosis is reserved as the virus passes through the placenta and cause fetal malformations in the first trimester of pregnancy and may induce premature birth in the last trimester of pregnancy. Also, especially B virus may cause fetal death in utero.Associated task to meet infectious jaundice in leptospirosis, salmonellosis, brucellosis and spirochetozei.

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