Freckle

FreckleFreckles Synonyms: efelide, macula solaris
Or efelidele Freckles are small patches, thin skin surface. They are usually multiple in number. With exposure to sunlight and therefore become more apparent in winter months are almost imperceptible. Although efelidele are predominantly benign can be observed in association with systemic disease.
People who are genetically succeptibile somatic mutations in melanocytes may have to promote the growth of epidermal melanogenesis. Melanocytes are increased in number and even that number may be low. With exposure to ultraviolet A and B increases dopa reaction leading to production of large melanosomes and characteristic clinical appearance.Efelidele occur during childhood as areas of increased pigmentation confined to regions of the body above the waist. At more advanced ages their number decreases. Efelidele appear at age 2 years and increase in number during adolescence. Macules are asymptomatic, more numerous in areas exposed to sun and fade, little in the winter.
Physical ExemenEfelidele are many simple, small, thin patches 1-5 mm in diameter with uniform pigmentation. It is commonly found on sun-exposed areas such as nose, cheeks, shoulders and upper back. Macules may be discrete or confluent. Similar simple sunburn freckles freckles are darker, and irregular edges of a few centimeters.Efelidele are common in people blondes and redheads. Are distributed equally between sexes. Can this be some impact on cosmetic and are not associated with increased mortality. Mortality may be increased in diseases associated with efelide such as xeroderma pigmentosum.
Causes and risk factors for frecklesFreckles tend to be inherited autosomal dominant. Are more common in people with lighter skin and thin and blond or red hair. Individuals succeptibile ultraviolet sun exposure induces pistruiii A and B by stimulating melanocytes to produce melanin.
Xeroderma pigmentosum. Freckles and even prominent blacks in heterozygous carriers of the disease autosomal recessive. Excessive Their appearance suggests the possibility of people with black hair disease. Neurofibromatosis. Freckles can be found in regions with folds of skin in individuals with this autosomal dominant disease.
Treatment of frecklesTreatment is not necessary. If the patient wants to change the cosmetic appearance indicate avoiding exposure to sun and makeup. SPF creams can be used to prevent efelidelor pigmentation caused by sun exposure. If you want you can try chemical peels, cryotherapy and laser treatment to make less efelidele poeminente. Efelidele cosmetic problem but may be associated with any complications. However, recent studies show that people with different skin types to efelide succeptibile are at increased risk of developing skin cancers. This combination is simply because efelidele and skin cancer are more common in people exposed to the sun with skin type I and II towards other people.