Thursday, June 23, 2011

Neonatal infections - Neonatal infection with varicella-zoster

The incidence of this disease is 0, 5-5 / 10. 000 newborns.
Transplacental transmission of infection is rarely, perinatal in 25%when the mother presents acute infection in the first 10 days of birth.
Mortality is 30% in perinatal infection.

Clinical signs are different. Congenital varicella is rare, occurs when maternal infection occurs during the first trimester and is associated with abnormalities of the central nervous system (CNS)and eye abnormalities.
Chickenpox is generally contacted postnatal average shape, rarelysevere, disseminated if it is exposed immediately after birth

Curative treatment is oral acyclovir at a dose of 30mg/kgc / day for7days.
The use and specific immunotherapy with immunoglobulin, 125units managed by a dose intra-muscular.

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