Wednesday, November 7, 2012

Vitamin D and brain function

Vitamin D and brain functionDesire to prevent skin cancer caused unexpected consequences-affecting brain function due to vitamin D deficiency "sunshine vitamin" is synthesized in human and animal skin when exposed to direct sunlight. Although it is well known for promoting bone health and regulating calcium levels (hence vitamin D supplementation of milk) seem to not be aware of all the benefits. Scientists have linked the nutrient-soluble hormone activity of a number of body functions, including the brain and.It's long as there are receptors for the vitamin in the central nervous system and in the hippocampus and that this activates and deactivates enzymes in the brain and CSF, involved in the synthesis of neurotransmitters and nerve growth. In addition, animal studies and the laboratory suggest that vitamin D promotes and reduce inflammation.
The researchers found that lower levels of vitamin D have negative effects on performance of performing a series of mental tests directly proportional. Compared with individuals with optimal levels of vitamin D deficient people were twice as cognitive disorders. Although it is known that low levels of vitamin D is associated with cognitive impairment is not known whether the high or normal cognitive reduce these losses and if taking supplements will help to regain such lost brain functions.Although cognitive impairment is often a precursor to dementia and Alzheimer's disease, vitamin D is a hot topic among researchers these pathologies.
So quoting Vitamin D is recommended? Experts say that from 1000 to 2000 IU daily-the amount that synthesizes body after 15-30 minutes of sun exposure two to three times a week for healthy adults. However, skin color, lifestyle and exposed skin surface affects the production of vitamin D.
Prenatal vitamin D may influence language development in children:Results of a large study suggests that maternal vitamin D levels during pregnancy affect neurocognitive development of children. The study shows that pregnant women with serum vitamin D insufficient (below 46 nmol / L) has a risk of about 2 times more likely to have a child with clinically significant language difficulties compared to women whose vitamin D level is greater than 70 nmol / L.These results match the already known information on the importance of vitamin D in fetal development. Scientists are doing randomized controlled trials to determine whether vitamin D supplements during pregnancy help promote an optimal neuropsychological development of the newborn.
Maternal vitamin D insufficiency during pregnancy is associated with the development of a number of prognosticuri bad for the child, including inadequate fetal growth, poor bone constitution and asthma in childhood. Yet very little is known about maternal vitamin D status and neuropsychological development of the newborn.The only study that investigated patterns of child development found no effect of maternal vitamin D insufficiency. But it was a rather limited scale study allowed the researchers to conclude on whether maternal vitamin D insufficiency during pregnancy or not effects on behavior and child language development.The new study recently examined twice the number of pregnant women involved in the first study and showed a link between maternal vitamin D insufficiency and language impairment in children of these mothers.It seems that maternal vitamin D insufficiency affects the evolution of normal brain development in children. Vitamin D has certain biological functions that are important for neurodevelopment, including promotion of cell division and protection against neurotoxins. New research want to know the exact biological mechanisms that can bind vitamin D insufficiency in the mother and abnormal brain development. The weakness of the study is that it followed the evolution of neuropsychological only children aged between 5 and 10 years.
Low levels of vitamin D can lead to depression?A large study conducted on adults suggests a strong link between low vitamin D levels and depressive symptoms, especially in individuals with a history of depression. Because the relationship between vitamin D and depression was significantly lower in patients with a history of this disease can be more than a marker of relapse of debuts. Surveillance of patients with depression and those with low levels of vitamin D in the body can be useful. The study was published in 2011 in the journal Mayo Clinic noimbrie and involved 12. 594 participants with an average age of 51 years. A total of 1563 individuals had a history of depression and 11. 031 no.The high level of vitamin D is associated with decreased risk of depression recurrence. The risk decreased by approximately 1% for each 10ng/ml increase vitamin D reduce the risk was not significant for those with no history of depression.Doctors say it is biologically plausible theory that vitamin D may play a role in depression. This seems to be an important factor in brain health and may be involved in the pathogenesis of depression.Risk factors for depression are not well understood but appears to involve gnetica and the environment. The obese have a higher risk of depression, and those diagnosed with diseases such as cancer, cardiovascular disease and multiple sclerosis may develop depression.
Sun exposure and risk of depression: no studies reported that the risk of depression associated with UVB light, however, may increase symptoms of depression during winter, known as seasonal affective disorder.Community-elderly residents of the Netherlands with major or minor depression had serum vitamin D levels 14% lower than those without depression.Italian women, women with low levels of vitamin D-sub 20 ng / ml had a two times higher risk of developing depression for men at increased risk by 60%-Postmenopausal women with vertebral fracture by 20% compaction had more depressive symptoms than those without fracture, women with at least 3 astfeld's fracture had an increased frequency of depression 3 times-Syrian women with cardiovascular disease, hypertension or kidney disease are 3 times more likely to be depressed, men with rheumatism and respiratory disease have an increased risk of depression vitamin D level is a risk factor for these diseases-History of depression is associated with late development of Alzheimer's disease, studies show that vtamina D is a risk factor in this disease.Vitamin D acts by reducing the risk of diseases that can trigger depression, such as cancer, cardiovascular disease and multiple sclerosis and reducing the production of cytokines, proteins that increase inflammation and are a factor in depression.
Vitamin D deficiency associated with dementia and Alzheimer's:Elderly men and women with low levels of vitamin D are 4 times more likely to have problems with memory, attention and logic, after a new study presented. It suggests a link between vitamin deficiency and increased risk of cognitive decline with dementia during life. Most old people in the world have deficient levels of vitamin D. It is suspected that this vitamin-hormone helps cleanse toxins from the brain to break ajtind amyloid-beta protein, a substance that plays a role in determining Alzheimer's disease. Elderly patients with low levels of vitamin D performed poorly on tests of logic and memory than those with adequate levels. Those with severely impaired levels experienced a substantial decline in thinking and execution functions, ability to organize thoughts, make decisions and make plans. The link between vitamin and cognitive decline persisted even after adjusting diet and general health and other factors.

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