Thursday, November 15, 2012

Substitutes drugs


Substitutes drugs

Bupropion (Zyban) - is the first drug that does not contain nicotine whose effectiveness has been proven scientifically. It is also the first product that can be taken in tablet form. Bupropion belongs to the class of antidepressant drugs and is marketed under the name Zyban. Substance acts on dopamine receptors. There are contraindications to the use of bupropion, and possible side effects. Medicine is released on prescription.
Substitutes drugs
FDA approved new drugs used in tobacco withdrawal works by blocking nicotinic receptors in the brain. Thus, smoking will not cause a sensation of pleasure, and smokers are able to quit easily.
For example varenicline (Chantix) is taken twice a day. Once inside the body, varenicline is fixed on nicotine receptors in the brain, reducing the feeling of pleasure caused by smoking and reduces withdrawal symptoms. Some studies have shown that varenicline increases by 50% the chances of smokers quit smoking. Other studies suggest that varenicline is more effective than bupropion, at least in the short term.
Side effects of varenicline are: headache, nausea, vomiting, sleep disorders, flatulence and taste perversion. Overall, varenicline is well tolerated.
Other drugs have shown some effectiveness in tobacco withdrawal, but to a lesser extent than bupropion and cause serious side effects. For these reasons, they are prescribed only if bupropion is ineffective. These are: Clonidine (antihypertensive), buspirone (an anxiolytic, in the presence of symptoms of anxiety), moclobemide and nortriptyline (antidepressants).
Substitutes drugs
Quitting smoking is the most important decision that smokers can take to improve the quality of life and life expectancy.
Quitting smoking is not easy. To have as much chance of success, smokers should know the benefits, the difficulties they face and the options available.

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